| Pair Name | Sulforaphane, Doxorubicin | ||
| Phytochemical Name | Sulforaphane (PubChem CID: 5350 ) | ||
| Anticancer drug Name | Doxorubicin (PubChem CID: 31703 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Drug Name | Doxorubicin |
| Adverse Reactions | Nausea, vomiting, diarrhoea. This was inferred cold nature anticancer drug. |
| Recommendations | Hot: Ligusticum chuam; Angelica sinensis; Zingiber officinale; Panax ginseng; Pogostemon cablin |
| Reference | ADReCS-Target: target profiles for aiding drug safety research and application. Nucleic Acids Res. 2018 Jan 4;46(D1):D911-D917. doi: 10.1093/nar/gkx899. ref_link |
| Pair Name | Sulforaphane, Doxorubicin | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Biological Phenomena | Induction-->Mitosis | |||
| In Vitro Model | MDA-MB-231 | Breast adenocarcinoma | Homo sapiens (Human) | CVCL_0062 |
| MCF-10A | Healthy | Homo sapiens (Human) | CVCL_0598 | |
| In Vivo Model | The 2×10⁵ 4T1 cells from in vitro culture in 0.05 mL PBS were injected into the mammary fat pad. | |||
| Result | Anticancer effect and safety of doxorubicin and nutraceutical sulforaphane liposomal formulation in triple-negative breast cancer (TNBC) animal model | |||
| No. | Title | Href |
|---|---|---|
| 1 | Anticancer effect and safety of doxorubicin and nutraceutical sulforaphane liposomal formulation in triple-negative breast cancer (TNBC) animal model. Biomed Pharmacother. 2023 May;161:114490. doi: 10.1016/j.biopha.2023.114490. | Click |
